- The Center for Neurosciences (CFN) . . .
. . . at The Feinstein Institute for Medical Research is pioneering in the use of brain imaging for making accurate and specific diagnoses of neurodegenerative diseases, charting their progress, and developing effective therapies to slow, halt, or reverse them. More precisely, the mission of the Center for Neurosciences is to elucidate neurobiological mechanisms underlying neurodegenerative disorders.
To study those underlying mechanisms, CFN investigators apply advanced multimodal brain-imaging technology to quantify progressive substrate abnormalities in a variety of populations. Those populations include patients with Parkinson’s disease (PD), Huntington’s disease (HD), and dystonia, as well as healthy volunteers. The availability of highly diverse cohort populations from throughout the New York metropolitan region,
through the North Shore-LIJ Hospital System, makes it possible for CFN investigators to characterize imaging biomarkers specific to the various phenotypes and genotypes among these disorders. Once an imaging biomarker can be reliably identified and validated, it becomes an important tool for improving early differential diagnosis, assessing the rates of disease progression, and evaluating the efficacy of novel experimental therapies.
Some of the biomarkers studied by CFN investigators have been shown to be more sensitive than the best currently accepted clinical methods for tracking the onset and development of diseases such as Parkinson’s—and the biomarkers are far less prone to error and subjective bias.