Investigators at the Center for Neurosciences use a wide variety of computational tools to analyze brain imaging data. Our overall goal is to extract important information directly reflecting cerebral function in normal subjects and patients with neurological disorders. 'Scanvp' is a software system incorporating many essential features for effective image display and analysis. Working in a PC environment, it provides a universal platform in conjunction with Matlab. 'Scanvp' allows image conversion from scanner (PET/MRI) to Analyze format. It can create any volume of interest (VOI) template in brain space and generate time course of functional activity in any set of regions of interest (ROI). This data can then be analyzed by a number of algorithms to estimate biological parameters. The parametric analysis is based on input functions derived from arterial blood sampling or appropriate reference tissue. This can be done on regional data or on a voxel basis to produce 3D parametric maps.In addition to generating 3D color graphics and visualizations, this software allows one to manipulate and edit image files. It offers many options to perform algebraic operations on images. 'Scanvp' also builds a common interface to run other popular statistical programs. These include univariate Statistical Parametric Mapping (SPM) program and multivariate packages such as Scaled Subprofiling Modeling (SSM) and Partial Least Squares (PLS). To obtain this software we ask that a potential user 'register' first in order to create a mailing list. This also helps us coordinate any bugfixing effort and provide necessary consultation. You will then be prompted to download a self-extracting zip file. Any user can install it based on instructions (readme.txt).